Parvus is pioneering a novel class of disease-modifying therapeutics – Navacims™ – that represent a paradigm shift in the way that autoimmune diseases are treated. Current approaches generally require broad suppression of the immune system to prevent immune attack against a patient’s own tissues. In contrast, our Navacim drug candidates are able to selectively blunt the action of pathogenic immune cells (including cytotoxic T cells and antigen-presenting cells), thereby restoring immune tolerance and potentially reversing disease.

Parvus has entered into a worldwide collaboration and license agreement with Genentech, a member of the Roche Group, to develop, manufacture, and commercialize novel Navacim™ therapeutics for the treatment of inflammatory bowel disease (IBD), autoimmune liver diseases (ALD), and celiac disease (CD).