Autoimmune diseases refer to a group of approximately 100 different diseases in which the body’s immune system, mistakenly attacks and destroys a patient’s own tissue and/or organ (self). There is currently no cure for autoimmune diseases, and current treatments rely on general, non-specific suppression of immune system function, frequently resulting in unacceptable side effects including infection and cancer.

There is a large unmet need for improved treatments that can suppress immune activity (restore immune tolerance) to specific organs without causing generalized immune suppression.

Navacims create organ-specific immune suppression, while avoiding the general immune suppression associated with current therapies. Parvus’ innovative approach has the potential to benefit millions of patients suffering from different autoimmune diseases and chronic inflammatory conditions.

Navacims reprogram disease-associated, autoantigen-experienced T cells (effectors) to differentiate and expand into regulatory T (Treg) cells (suppressors) specific to the diseased organ. These organ-specific Tregs selectively reverse autoimmune disease by suppressing autoimmune attacks on self without impairing normal immune function.

Parvus is advancing our robust pipeline of proprietary Navacim drug candidates towards clinical testing. Parvus’ leadership team possesses deep experience in drug discovery, development, and commercialization in diverse disease areas, including immunology and autoimmune disease.

Jord Cowan
Vice President of Operations
Louis Demers
Senior Vice President CMC
Sarah Grimberg
Senior Director Clinical Operations
Murray Hinz
Senior Vice President of Finance and Administration
Steve Levin
Vice President, Translational Immunology
Pere Santamaria, PhD, MD
Founder & Chief Scientific Officer, Board Member
Peter Strumph
Chief Executive Officer, Board Member
Hugh Young Rienhoff, Jr. MD
Executive Chairman
Pere Santamaria, PhD, MD
Founder & Chief Scientific Officer, Board Member
Peter Strumph
Chief Executive Officer, Board Member
Matthew J. Hogan, MBA
Charles Johnson, MB.ChB, FCP (SA)
Daniel C. Adelman, MD
Louis
Ed
Ben
Vanessa
Steven
Lesiena
Leo
Joel
Chris L
Murray
Rolando
Wing
Jord
Peter
Janelle
Mia
Jonathan
Alex
Sarah

If you are interested in discussing a collaboration or partnership opportunity, contact info@parvustx.com.